Bloodworks
Hormones6 min read·

Testosterone testing: what it measures and when it makes sense

Fatigue, reduced libido, or muscle loss: testosterone is quickly identified as the cause. But a blood test tells you far more than any self-diagnosis ever can.

Medically reviewed by the Bloodworks medical team

In short

  • Testosterone affects muscle mass, fat distribution, bone density, libido, mood and energy.
  • In men the level declines gradually with age, which is normal.
  • The complaints are non-specific and also fit dozens of other causes.
  • Testosterone is highest early in the morning, so the time of the blood draw matters.

What you can measure

Not every cause is visible in blood. These are the values that most often explain something.

Recommended test

Aanbevolen bij vermoeidheid, minder libido of verlies van spiermassa

Essential Hormones Male

5 markers

Een totaalwaarde alleen zegt te weinig. Dit pakket meet testosteron, vrij testosteron, SHBG, LH en FSH in één afname, waardoor de waarde in samenhang beoordeeld kan worden. Een ochtendprik geeft het meest representatieve beeld.

  • Personal assessment by a registered doctor
  • Clear laboratory report, in plain language
  • No referral needed
  • 800+ blood draw locations

159

Plus 29,- blood draw fee per order, free from 225,-.

View this test

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What does testosterone do in the body?

Testosterone is the primary male sex hormone, but also plays a role in women. It drives muscle mass, fat distribution, bone density, libido, and partly also mood and energy. In men, it is produced mainly in the testes; in women, in the ovaries and adrenal glands.

In men, levels decline gradually with age, on average around one to two per cent per year from the age of thirty. This is normal and proceeds without noticeable symptoms in most men. A level that is notably low for one's age, or that is falling faster than expected, is a different matter.

Complaints that people associate with low testosterone

The classic complaints are fatigue, reduced libido, loss of muscle mass, and mood problems. But virtually all of these complaints are non-specific: they can have dozens of other causes, such as:

  • sleep deprivation
  • thyroid problems
  • low iron
  • chronic stress

All of these can produce the same symptoms as a low testosterone level.

Symptoms are not enough. A doctor assessing testosterone complaints always looks at the blood value in combination with age, the history of symptoms, and other markers such as LH and SHBG. Without measurement, there is no diagnosis.

What does a testosterone test measure?

Total testosterone in the blood is the most commonly measured. But testosterone is partly bound to proteins in the blood, only free testosterone is biologically active. SHBG (sex hormone-binding globulin) largely determines how much testosterone is freely available.

In a complete hormone panel, both are measured, alongside LH and FSH (hormones from the brain that drive production) and oestradiol.

The time of the blood draw matters: testosterone is at its highest early in the morning. A measurement later in the day can give a lower value without there being a deficiency. Bloodworks recommends a morning blood draw for the most representative measurement.

Want to have your hormone values measured?

The Essential Hormones Male package measures testosterone, free testosterone, SHBG, LH, and FSH in a single blood draw.

View Essential Hormones Male →

In women: testosterone as part of the hormonal picture

Women can also experience symptoms from a low testosterone level, reduced libido, fatigue, muscle loss. Measuring testosterone in women has a different reference frame than in men.

The female hormone panel typically combines testosterone with oestradiol, progesterone, LH, FSH, and prolactin, together these give a complete picture of hormonal balance.

Sources

Recommended test

Aanbevolen bij vermoeidheid, minder libido of verlies van spiermassa

Essential Hormones Male

5 markers

Een totaalwaarde alleen zegt te weinig. Dit pakket meet testosteron, vrij testosteron, SHBG, LH en FSH in één afname, waardoor de waarde in samenhang beoordeeld kan worden. Een ochtendprik geeft het meest representatieve beeld.

  • Personal assessment by a registered doctor
  • Clear laboratory report, in plain language
  • No referral needed
  • 800+ blood draw locations

159

Plus 29,- blood draw fee per order, free from 225,-.

View this test

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